This course offers a description of the nervous system's structure and function in terms of molecular processes. Topics are developed through lectures, discussions and student presentations. The course begins with a brief introduction to general and organic chemistry, then continues with the following topics: neurocellular anatomy and the biochemistry of cell neurotransmitters and receptors, and the biochemistry of psychoactive drugs and neurological disorders. This course is a required core course for the Neuroscience Concentration, and with CHEM 108 or CHEM 110 fulfills the natural science distribution requirement. No prerequisites.

This course provides a thorough introduction to the fundamental concepts, theories, and methodologies of chemistry. Topics may include stoichiometry, theories of molecular structure and bonding, the periodic table, acid-base chemistry, chemical equilibria, and thermodynamics. This course provides a basis for the further study of chemistry. The format is lecture and discussion. Prerequisites: for first-year students, chemistry readiness test and survey; none for other students.

This course provides a thorough introduction to the fundamental concepts, theories, and methodologies of chemistry. Topics may include stoichiometry, theories of molecular structure and bonding, the periodic table, acid-base chemistry, chemical equilibria, and thermodynamics. This course provides a basis for the further study of chemistry. The format is lecture and discussion. Prerequisites: for first-year students, chemistry readiness test and survey; none for other students.

This course covers a full year of chemistry in one semester, and is designed for students with previous study of chemistry. We will explore and review key principles and methods from both CHEM 121 and CHEM 124. Pre-requistie: Placement exam. Corequisite: CHEM 123.

This laboratory course accompanies CHEM 121 and 122 with an introduction to modern experimental chemistry. Laboratory experiments explore inorganic synthesis, molecular structure and properties, and spectroscopy, with an emphasis on laboratory safety, computerized data acquisition and analysis, and the theory of analytical instrumentation. The laboratory work is organized around individual and team projects. Communication skills are developed through proper use of a laboratory notebook. One three-hour laboratory is held per week. Corequisite: CHEM 121 or 122. Juniors and seniors may enroll with permission of department chair.

This laboratory course accompanies CHEM 121 and 122 with an introduction to modern experimental chemistry. Laboratory experiments explore inorganic synthesis, molecular structure and properties, and spectroscopy, with an emphasis on laboratory safety, computerized data acquisition and analysis, and the theory of analytical instrumentation. The laboratory work is organized around individual and team projects. Communication skills are developed through proper use of a laboratory notebook. One three-hour laboratory is held per week. Corequisite: CHEM 121 or 122. Juniors and seniors may enroll with permission of department chair.

This laboratory course accompanies CHEM 121 and 122 with an introduction to modern experimental chemistry. Laboratory experiments explore inorganic synthesis, molecular structure and properties, and spectroscopy, with an emphasis on laboratory safety, computerized data acquisition and analysis, and the theory of analytical instrumentation. The laboratory work is organized around individual and team projects. Communication skills are developed through proper use of a laboratory notebook. One three-hour laboratory is held per week. Corequisite: CHEM 121 or 122. Juniors and seniors may enroll with permission of department chair.

This laboratory course accompanies CHEM 121 and 122 with an introduction to modern experimental chemistry. Laboratory experiments explore inorganic synthesis, molecular structure and properties, and spectroscopy, with an emphasis on laboratory safety, computerized data acquisition and analysis, and the theory of analytical instrumentation. The laboratory work is organized around individual and team projects. Communication skills are developed through proper use of a laboratory notebook. One three-hour laboratory is held per week. Corequisite: CHEM 121 or 122. Juniors and seniors may enroll with permission of department chair.

This lecture course offers a study of the chemical and physical properties of organic compounds. Theoretical principles are developed with particular emphasis on molecular structure and reaction mechanisms. The descriptive aspects of organic chemistry include strategies for synthesis and the study of compounds of biochemical interest. Prerequisites: CHEM 126, or permission of department chair. Also requires a grade of C+ or higher in CHEM 121 or CHEM 122.

This laboratory course introduces fundamental methods of purification such as extraction, distillation, recrystallization, and column chromatography. Experiments include the isolation of a natural product, oxidation and reduction reactions, and an examination of E1 and E2 reactions. Compounds are identified and assessed for purity by melting point determination, refractometry, gas chromatography, infrared spectroscopy, and proton nuclear magnetic resonance. Corequisite: CHEM 231.

This laboratory course introduces fundamental methods of purification such as extraction, distillation, recrystallization, and column chromatography. Experiments include the isolation of a natural product, oxidation and reduction reactions, and an examination of E1 and E2 reactions. Compounds are identified and assessed for purity by melting point determination, refractometry, gas chromatography, infrared spectroscopy, and proton nuclear magnetic resonance. Corequisite: CHEM 231.

This laboratory course introduces fundamental methods of purification such as extraction, distillation, recrystallization, and column chromatography. Experiments include the isolation of a natural product, oxidation and reduction reactions, and an examination of E1 and E2 reactions. Compounds are identified and assessed for purity by melting point determination, refractometry, gas chromatography, infrared spectroscopy, and proton nuclear magnetic resonance. Corequisite: CHEM 231.

This course presents a study of chemical kinetics and chemical thermodynamics. Specific topics include rate laws and reaction mechanisms, reaction-rate theories, the laws of thermodynamics, thermochemistry, properties of solutions, and equilibrium. Applications will be drawn from organic, and inorganic chemistry, as well as biochemistry. Prerequisites: CHEM 126. MATH 112 is highly recommended.

Is your water safe? How do you know what compounds are in your water, food, body, and local environment? How do you measure and quantify these compounds? How do you convince yourself that your measurements are valid or invalid? CHEM 341 is a hybrid lecture/laboratory course on the theory and practice of quantitative chemical analysis. Students will apply fundamental principles of measurement, instrument design, and data analysis to instrumental methods. After applying these principles to a sequence of laboratory experiments, students will then develop and evaluate their own instrumental methods. Topics include spectroscopic, electrochemical, and chromatographic methods. According to student interest, additional topics may include environmental analysis, biochemical assays, food quality, and consumer safety. Prerequisite: four semesters of CHEM lab or permission of the instructor.

This course is an introduction to fundamental laboratory technicques in biochemistry. The focus of the course is the isolation, purification, characterization and detailed kinetic analysis of alkaline phosphatase from E. coli. This course meets for one three-hour laboratory period per week. Prerequisite or corequisite: CHEM 256.

In this laboratory course, students will engage in projects that integrate inorganic synthesis, analytical instrumentation, and physical measurement, focusing on coordination complexes. The course meets for one three-hour laboratory period per week. Prerequisite: CHEM 234 or permission of instructor.

Section 01 (.25 unit) Students engage in independent research under the direction of a faculty mentor. The time requirement is at least three hours in lab per week. Students will learn to search the literature and give professional presentations. This course also provides an introduction to scientific writing. More details can be obtained from the department chair. Prerequisite: permission of the instructor.
Section 02 (.5 unit). This section is a prerequisite to Chemistry 497-498 (Senior Honors). The time commitment is six to eight hours per week in lab. Students will learn to search the literature and give professional scientific presentations as well as to write scientifically. More details can be obtained from the department chair. Prerequisite: permission of instructor.

Selected topics in advanced chemistry and biochemistry are explored with an emphasis on reading and discussing current scientific research and literature. Prerequisite: CHEM 234 or permission of the instructor unless otherwise indicated.

Biophysical Chemistry Seminar
Section 01 This seminar focuses on understanding some of the thermodynamics associated with bio-macromolecules like proteins and DNA. We may examine transport processes, the thermodynamics that characterize the intra- and intermolecular interactions, and some of the statistical models that are used to understand folding and structural transitions. (Instructor: Hemkin)

Advanced Organic Chemistry Seminar
Section 02 Selected topics in organic chemistry are covered with an emphasis on advanced spectral methods of identifying organic compounds and modern methods of organic synthesis. (Instructors: Getzler, J. Hofferbeth)

Art and Chemistry Seminar
Section 03 This seminar focuses on understanding some of the relationships between art and chemistry, for example, the chemical basis of pigmentation and the use of chemical techniques to identify works from unknown origins. (Instructor: Hemkin)

Chemical Biology Seminar
Section 04 Chemical biology is a scientific discipline at the interface of chemistry and biology. This seminar explores the applications of chemical techniques to manipulate and investigate biological systems. Using resources including current literature, this course covers the chemical techniques used to understand and treat diseases such as cancer and viral, microbial, and neurodegenerative diseases. (Instructor: Hunsen)

Hydrogen Energy Systems Seminar
Section 05 In the search for abundant, renewable, and carbon-free energy sources, scientists are on a quest to develop inexpensive and renewable methods to produce, store, and use hydrogen fuel. This seminar explores various aspects of hydrogen energy systems, including: the development of a "hydrogen economy" infrastructure; hydrogen production from fossil fuel reforming and from water splitting; solid-state storage materials; hydrogen fuel cell operation and design; and advanced research directions in hydrogen energy. (Instructor: Cummings)

Enzyme Mechanism Seminar
Section 06 Over the past two decades, our collective knowledge base in chemical biology has exploded. One powerful approach to organizing this enormous body of information is to recognize that nature is bound by the same principles that govern chemistry. Students will explore the mechanistic logic behind biological pathways and examine the technical aspects of how reasonable enzyme mechanisms are determined. (Instructor: J. Hofferberth)

Emerging Techniques in Biological Chemistry
Section 07 Recent advances in biotechnology have had a huge impact on the ability to detect and analyze micro- and nano-size biomolecules with greater accuracy. This literature-based course will look at several emerging techniques and instrumentation that are being used to advance research in topics such as protein dynamics, single molecule detection, and metabolic engineering in areas that range from neuroscience to biofuels. (Instructor: Rouhier)

Advanced Biochemistry
Section 08 We will explore the molecular details of key metabolic pathways, biological signaling, and molecular transport machinery.The topics discussed will be valuable to students on a trajectory toward careers in life science research and medicine. Students will engage the primary literature to explore current research related to the topics discussed. This course will dovetail with and extend the topics taught in Biochemistry CHEM 256.Prerequisite: CHEM 256 (Instructor: Hofferberth, Rouhier)

This is a required course for all chemistry majors, including those involved in independent research. The course covers topics relating to chemistry research. Weekly meetings will involve (1) searching chemistry literature, (2) analyzing primary research articles, and (3) discussing ethics, trends, funding, and other issues relating to chemistry research. During the semester, students will give written and oral presentations of primary research articles. Prerequisite: senior standing.

The emphasis is on independent research in collaboration with a faculty mentor, culminating with a thesis that is defended orally to an outside examiner. Prerequisites: GPA of at least 3.2, enrollment in Section 02 of CHEM 375 or CHEM 376, and permission of department chair. See department chair or Web site for full description.